Osteoarthritis will also be modeled in mice by destabilization on the medial meniscus by surgically sectioning a ligament from the joint. The CB2 receptor agonist HU308 diminished joint injury in the DMM osteoarthritis design, While CB2 (−/−) mice produced extra joint problems than wild- style mice (Sophocleous et al, 2015). https://landenxflck.blue-blogs.com/39979568/rumored-buzz-on-endocannabinoid-system