Mutations in Wnt-signaling coreceptor LRP6 have been linked to coronary artery disease (CAD) by unknown mechanisms. Here. we show that reduced LRP6 activity in LRP6R611C mice promotes loss of vascular smooth muscle cell (VSMC) differentiation. leading to aortic medial hyperplasia. https://www.bekindtopets.com/great-pick-Nobivac-Feline-1-HCPCh-special-find/