There's a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to reduce afferent pain transmission and generate analgesia. Consequently, medicines like clonidine that focus on alpha-two receptors can impact the transmission of pain. Jun 10, 2024 · If clonidine therapy https://hillarym805fdz6.glifeblog.com/profile