Tramadol and its metabolite, O-desmethyltramadol (M1), are current in human milk. There is no info on the results from the drug around the breastfed toddler or the effects in the drug on milk generation. The M1 metabolite is more powerful than tramadol in mu opioid receptor binding [see Clinical Pharmacology https://torreyt197bhm2.blogozz.com/profile