Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors inside the central nervous method, conolidine modulates alternate molecular targets. A Science Innovations study identified that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://bookmarkmoz.com/story20621428/what-does-alternative-natural-pain-relief-to-replace-traditional-painkillers-mean